MUSIC

Mitochondrial DAMPs as mechanistic biomarkers of gut mucosal inflammation.

A project by the Gut Research Unit

Centre for Inflammation Research
Queen's Medical Research Institute
Edinburgh, UK

Jon Rysdale, Patient Representative

on what this study is about and why you should consider taking part.

Kris Gourlay, Patient Representative

shares his perspective on the study.

Patient Information Sheets

Summary Full

Updates

Welcome to our new PPI member Aerin Thompson

I'm Aerin, a first year PhD student at The University of Edinburgh studying inflammation resolution and tissue repair.

I was diagnosed with Ulcerative Colitis back in 2014 under paediatric care. I was experiencing severe symptoms before being admitted to hospital through A&E where I was monitored for four weeks.

I like to be active and row for the university high performance team alongside my studies. Originally from Nottingham, I am enjoying the views that Edinburgh and Scotland have to offer.

8 March 2023

Scottish Society of Gastroenterology Winter Meeting December 2022

Dr Rebecca Hall recently presented our work linking patient-reported well-being as a potential marker for our scientific biomarker studies

Abstract Powerpoint Slides

28 December 2022

Molly Halligan has joined our Patient Public Involvement team

Listen to her experience in taking part in IBD research.

29 November 2021

Read Kris' Story Here

Kris is one of our study's patient representative and he shares his story with The Herald here. His experience and views help us shape the design and conduct of our research.

29 June 2021

Tweets by Edin_IBDScience

What is the MUSIC study?

The MUSIC study is an observational study where participants are followed up closely every 3 months for a year.

During this follow-up period, extra blood and stool samples are taken for scientific analyses. Participants will also be offered an extra colonoscopy to check for mucosal healing.

We hope that this study will unlock new scientific insights into inflammatory bowel disease.

Our Research

We want to investigate how damage-associated molecular patterns (DAMPs) or ‘danger signals’ can be used as a biomarker test for patients with Crohn's disease or ulcerative colitis.

Why take part?

MUSIC runs in conjunction with your existing NHS treatment. It simply aims to monitor you much more closely as your condition hopefully improves.
It will be a learning opportunity for you. The more involved you are with your treatment, the more you will learn about your condition and how you can get back to full health as soon as possible.
You will be contributing to the latest research, the long term goal of which is to find more effective treatments and ultimately a cure for IBD.

Who can take part?

We are looking for patients:

Age 16 and above
Have Crohn's disease or ulcerative colitis
Referred by their NHS doctor
Edinburgh, Glasgow or Dundee

What is involved?

This is a 12-month follow-up study which will involve appointments at 3 monthly intervals. We plan to closely monitor your clinical progress in line with the scientific work which we will carry out.

During the follow-up period, we will be gathering information on how you are doing and this information will be shared with your treating NHS clinician.

This may allow them to make treatment adjustments and check on how you're doing more closely than usual. For full details, please read the patient information sheet linked here.

Start
3 months
6 months
9 months
12 months

Participating Centres

Edinburgh

Western General Hospital

Dundee

Ninewells Hospital

Glasgow

Queen Elizabeth University Hospital

Our Sponsors

Centre for Inflammation Research, University of Edinburgh